Wei Guo

Selected Peer-Reviewed Articles

Zhang Y, Gregorich ZR, Wang Y, Braz CU, Zhang J, Liu Y, Liu P, Shen J, Aori N, Hacker TA, Granzier H, Guo W. Disruption of the nuclear localization signal in RBM20 is
causative in dilated cardiomyopathy. JCI Insight. 2023 Jul 10;8(13):e170001. doi:
10.1172/jci.insight.170001. PMID: 37219949; PMCID: PMC10371347. (Highlighted in the Editor’s Picks; https://insight.jci.org/this-month/2023/8)

Zhang Y, Wang C, Sun M, Jin Y, Braz CU, Khatib H, Hacker TA, Liss M, Gotthardt M, Granzier H, Ge Y, Guo W. RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis. FASEB J.2022 May;36(5):e22302. PubMed PMID: 35394688;

Larson, Eli J., Gregorich, Zachery R., Zhang, Yanghai, Li, Brad H., Aballo, Timothy J., Melby, Jake A., Ge, Ying and Guo, Wei. ablation is associated with changes in the expression of titin-interacting and metabolic proteins. Mol. Omics, 2022, 18, 627-634

Sun, M.; Jin, Y.; Zhang, Y.; Gregorich, Z.R.; Ren, J.; Ge, Y.; Guo, W. SR Protein Kinases Regulate the Splicing of Cardiomyopathy-Relevant Genes via Phosphorylation of the RSRSP
Stretch in RBM20. Genes. 2022, 13, 1526. https://doi.org/10.3390/genes13091526

Liu Y, Ding Q, Guo W. Life Course Impact of Glucocorticoids During Pregnancy on Muscle Development and Function. Front. Anim. Sci. 2021; 2: 83-89; DOI: 10.3389/fanim.2021.788930.

Wang C, Zhang Y, Methawasin M, Braz CU, Gao-Hu J, Yang B, Strom J, Gohlke J, Hacker T, Khatib H, Granzier H, Guo W. RBM20S639Gmutation is a high genetic risk factor for premature death through RNA-protein condensates. J Mol Cell Cardiol. 2022; 165:115-129. PMID: 35041844.

Liu Y, Ding Q, Halderson, SJ, Arriola Apelo SI, Jones AK, Pillai SM, Hoffman ML, Reed SA, Govoni, KE, Zinn SA, Guo W. Maternal overnutrition during gestation in sheep alters autophagy associated pathways in offspring heart. Front. Genet. 2022, 12:742704. PMID:
35173761

Wei Guo, Chaoqun Zhu, Zhiyong Yin, Yanghai Zhang, Chunyan Wang, Andrea Sanchez Walk, Ying-Hsi Lin, Timothy A. McKinsey, Kathleen C. Woulfe, Jun Ren, and Herbert G.
Chew, Jr. The Ryanodine Receptor Stabilizer S107 Ameliorates Contractility of Adult Rbm20 Knockout Rat Cardiomyocytes. Physiol Rep. 2021, 9(17): e15011. PMID: 34523360

Maimaiti R, Zhu CQ, Zhang YH, Ding QY, Guo W. RBM20-mediated pre-mRNA splicing has muscle-specificity and differential hormonal responses between muscles and in muscle cell cultures. Int. J. Mol. Sci. 2021, 22(6), 2928; https://doi.org/10.3390/ijms22062928

Mohammadabadi M. Bordbar F, Jensen J, Du M, Guo W. Key Genes Regulating Skeletal Muscle Development and Growth in Farm Animals. Animals, 2021, 11, 835. https://doi.org/10.3390/ani11030835

Jay W Schneider, Saji Oommen, Muhammad Y Qureshi, Sean C Goetsch, David R Pease, Rhianna S Sundsbak, Wei Guo, Mingming Sun, Han Sun, Hidehito Kuroyanagi, et al. A ribonucleoprotein-granule pathway to heart failure in human RBM20 cardiomyopathy gene-edited pigs. Nature Medicine. 2020; 26(11): 1788-1800.

Farhad Bordbar, Just Jensen, Min Du, Abeid Adam, Wei Guo, Lingyang Xu, Huijiang Gao, Lupei Zhang, Junya Li. Identification and validation of a novel candidate gene regulating net meat weight in Simmental beef cattle based on imputed next-generation sequencing. Cell Proliferation. 2020; 53(9): e12870. PMID: 32722873

Zhi Li, Xiao-Lin Wu, Wei Guo, Jun He, Hao Li, Guilherme J. M. Rosa, Daniel Gianola, Richard G. Tait Jr., Jamie Parham, John Genho, Tom Schultz, Stewart Bauck. Estimation of
genomic breed composition of individual animals in composite beef cattle. Animal Genetics. 2020. 51(3): 457-460.

Hanfang Cai, Chaoqun Zhu, Zhilong Chen, Rexiati Maimaiti, Mingming Sun, Richard J. McCormick, Xianyong Lan, Hong Chen and Wei Guo. Angiotensin II influences pre-mRNA splicing regulation by enhancing RBM20 transcription through activation of the MAPK/ELK1 signaling pathway. Int. J Mol. Sci. 2019. 20(20): E5090. PMID: 31614708.  

Qiurong Wang, Chaoqun Zhu., Mingming Sun., Rexiati Maimaiti., Stephen P. Ford, Peter W. Nathanielsz, Jun Ren and Wei Guo.  Maternal obesity impairs fetal cardiomyocytes contractile function in sheep. FASEB J. 2019; 33(2): 2587-2598. PMID: 30289749.  

Selected Book Chapters

Guo Wei and Greaser, M.L. 2022. “Muscle Structure, Proteins and Meat Quality” in “New aspects of meat quality-from genes to ethics”, 2ed. Peter Purslow, Elsevier, Philadelphia,
PA, In Press

Greaser, M.L. and Guo Wei. 2011. “Post-mortem Muscle Chemistry” In: “Handbook of Meat and Meat Processing, Second Edition”, ed. YH Hui, CRC Press, Boca Raton, FL, pp70-78. 

Greaser, M.L. and Guo Wei. 2014. “Proteins” In “Handbook of Muscle Foods Analysis, Second Edition”, ed, Leo M.L.Nollet, Fidel Toldra, CRC Press, Boca Raton, FL, PP357-368 

Guo Wei and Greaser, M.L. 2016. “Muscle Structure, Proteins and Meat Quality” in “New aspects of meat quality-from genes to ethics”, ed. Peter Purslow, Elsevier, Philadelphia, PA, PP13-32