Robert Bremel

Dairy Science Emeritus Professor

Office Location

1675 Observatory Dr
Madison, WI 53706

Homan EJ, Bremel RD. Determinants of tumor immune evasion: the role of T cell exposed motif frequency and mutant amino acid exposure. Front Immunol. 2023 May 5;14:1155679. doi: 10.3389/fimmu.2023.1155679. PMID: 37215122; PMCID: PMC10196236.

Bremel RD, Homan EJ. Extensive T-Cell Epitope Repertoire Sharing among Human Proteome, Gastrointestinal Microbiome, and Pathogenic Bacteria: Implications for the Definition of Self. Front Immunol. 2015 Oct 22;6:538. doi: 10.3389/fimmu.2015.00538. PMID: 26557118; PMCID: PMC4617169.

Bremel RD, Homan EJ. Frequency Patterns of T-Cell Exposed Amino Acid Motifs in Immunoglobulin Heavy Chain Peptides Presented by MHCs. Front Immunol. 2014 Oct 28;5:541. doi: 10.3389/fimmu.2014.00541. PMID: 25389426; PMCID: PMC4211557.

Harms JS, Khan M, Hall C, Splitter GA, Homan EJ, Bremel RD, Smith JA. Brucella Peptide Cross-Reactive Major Histocompatibility Complex Class I Presentation Activates SIINFEKL-Specific T Cell Receptor-Expressing T Cells. Infect Immun. 2018 Jun 21;86(7):e00281-18. doi: 10.1128/IAI.00281-18. PMID: 29735518; PMCID: PMC6013681.

Høglund RA, Bremel RD, Homan EJ, Torsetnes SB, Lossius A, Holmøy T. CD4+ T Cells in the Blood of MS Patients Respond to Predicted Epitopes From B cell Receptors Found in Spinal Fluid. Front Immunol. 2020 Apr 9;11:598. doi: 10.3389/fimmu.2020.00598. PMID: 32328067; PMCID: PMC7160327.

Høglund RA, Lossius A, Johansen JN, Homan J, Benth JŠ, Robins H, Bogen B, Bremel RD, Holmøy T. In Silico Prediction Analysis of Idiotope-Driven T-B Cell Collaboration in Multiple Sclerosis. Front Immunol. 2017 Oct 2;8:1255. doi: 10.3389/fimmu.2017.01255. PMID: 29038659; PMCID: PMC5630699.

Høglund RA, Torsetnes SB, Lossius A, Bogen B, Homan EJ, Bremel R, Holmøy T. Human Cysteine Cathepsins Degrade Immunoglobulin G In Vitro in a Predictable Manner. Int J Mol Sci. 2019 Sep 29;20(19):4843. doi: 10.3390/ijms20194843. PMID: 31569504; PMCID: PMC6801702.

Homan EJ, Bremel RD. Are cases of mumps in vaccinated patients attributable to mismatches in both vaccine T-cell and B-cell epitopes?: An immunoinformatic analysis. Hum Vaccin Immunother. 2014;10(2):290-300. doi: 10.4161/hv.27139. Epub 2013 Nov 25. PMID: 24275080; PMCID: PMC4185895.

Homan EJ, Bremel RD. A Role for Epitope Networking in Immunomodulation by Helminths. Front Immunol. 2018 Jul 31;9:1763. doi: 10.3389/fimmu.2018.01763. PMID: 30108588; PMCID: PMC6079203.

Xu-Monette ZY, Li J, Xia Y, Crossley B, Bremel RD, Miao Y, Xiao M, Snyder T, Manyam GC, Tan X, Zhang H, Visco C, Tzankov A, Dybkaer K, Bhagat G, Tam W, You H, Hsi ED, van Krieken JH, Huh J, Ponzoni M, Ferreri AJM, Møller MB, Piris MA, Winter JN, Medeiros JT, Xu B, Li Y, Kirsch I, Young KH. Immunoglobulin somatic hypermutation has clinical impact in DLBCL and potential implications for immune checkpoint blockade and neoantigen-based immunotherapies. J Immunother Cancer. 2019 Oct 22;7(1):272. doi: 10.1186/s40425-019-0730-x. PMID: 31640780; PMCID: PMC6806565.