Laura Hernandez

Hernandez Lab / Lactation Biology @ UW-Madison

Professor Lactation Physiology; Affiliate Professor Obstetrics and Gynecology

Research, Teaching

Phone

608-263-9867

Office Location

1675 Observatory Dr
864A Animal Sciences
Madison, WI 53706

Post-Doctoral Fellow – Molecular and Cellular Physiology, University of Cincinnati (2008-2011)

PhD University of Arizona (2008)

Master’s of Science, New Mexico State University (2004)

Bachelor’s of Science, New Mexico State University (2002)

Selected Peer-Reviewed Articles

Vang AL, Dorea JRR, Hernandez LL. Graduate student literature review: mammary gland development in dairy cattle-quantifying growth and development. 2024. J. Dairy Sci. 107(12):11611-11620. Doi: 10.3168/jds.2024-25007. PMCID: PMC11614682.

Vang AL, Frizzarini WS, Webster HH, Cunha TO, Nelson KM, Dorea JRR, Hernandez LL. 2024. Ultrasound-assisted minimally invasive technique for tissue collection from bovine mammary glands. Vet. Med. Sci. Nov;10(6):e70027. Doi:10.1002/vms3.70027. PMCID:PMC11410675.

Connelly MK, Rodney RM, Kuehnl J, Andrade JPN, Andrade FS, Henschel S, Block E, Lean IJ, Hernandez LL. 2024. The effects of magnitude of calcium decline at the onset of lactation on serotonin dynamics and the serotonin-calcium axis. J. Dairy Sci. Oct 28; doi/10.3168/jds.2024-24836. Epub ahead of print.

Monteiro PLJ, Wiltbank MC, Frizzarini WS, Andrade JPN, Cabrera EM, Schoenfeld SG, Domingues RR, Hernandez LL. 2024. Biol. Reprod. Doi:10.1093/biolre/ioae133. Epub ahead of print. PMID: 39221747.

Desorcy-Scherer K, Zuniga-Chaves I, Resiner MA, Suen G, Hernandez LL. 2024. Investigating the influence of perinatal fluoxetine exposure on murine gut microbial communities during pregnancy and lactation. Sci. Rep. 14:13762. PMCID:PMC1178873.

Field SL, Galvan EA, Hernandez LL, Laporta J. 2024. Exploring the contribution of mammary-derived serotonin on liver and pancreas metabolism during lactation. PLoS One. 19(6):e0304910. PMCID: 1152252.

Frizzarini WS, Monteiro PLJ, Campolina JP, Vang AL, Soudah O, Lewandowski LR, Connelly MK, Apelo SIA, Hernandez LL. 2024. Mechanisms by which feeding synthetic zeolite A and dietary cation anion difference diets impact mineral metabolism in multiparous Holstein cows: Part I. J. Dairy Sci. 107(7):5204-4221. PMID:38490548.

Frizzarini WS, Campolina JP, Vang AL, Soudah O, Lewandowski LR, Teixeira NN, Connelly, MK, Monteiro PLJ, Hernandez LL. 2024. Mechanisms by which feeding synthetic zeolite A and dietary cation anion difference diets impact feed intake, energy metabolism, and milk performance: Part II. J. Dairy Sci. 107(7):5222-5234. PMID: 3840547.

Connelly MK, Harris RMR, Kuehnl J, Andrade JPN, Andrade FS, Henschel S, Block E, Lean IJ, Hernandez LL. 2024. Influence of prepartum dietary cation anion difference and the magnitude of calcium decline at the onset of lactation on mineral metabolism and physiological responses. J Dairy Sci. 107(2):1228-1243. PMID: 37769944.

Hernandez LL, McArt JAA. 2023. Perspective: Transient postparturient hypocalcemia-A lactation-induced phenomenon of high-producing dairy cows. J. Dairy Sci. 106(12):8177-8180. PMID:37641345.

Domingues RR, Teixeira NN, Frizzarini WS, Beard AD, Connelly MK, Vang AL, Wiltbank MC, Hernandez LL. 2023. The antidepressant fluoxetine (Prozac) modulates serotonin signaling to alter maternal peripartum calcium homeostasis. Sci. Rep. 13(1):21832. Doi: 10.1038/s41598-023.49253-4. PMCID: PMC10710465.

Fricke HP, Krajco CJ, Perry MJ, Desorcy-Scherer KM, Wake LA, Charles JF, Hernandez LL. 2023. Developmental fluoxetine exposure affects adolescent and adult bone depending on the dose and period of exposure in mice. Physiol. Rep. 11:e15881. doi.org/10.14814/phy2.15881. PMCID: PMC10687345.

Fricke HP, Krajco CJ, Perry MF, Brettingen LJ, Wake LA, Charles JF, Hernandez LL. 2023. Fluoxetine treatment during the postpartal period may have short-term impacts on murine maternal skeletal physiology. Front. Pharmacol. 14.1244580. doi: 10.103389/fphar.2023.1244580. PMCID: PMC10701399.

Fricke HP, Krajco CJ, Perry MF, Reisner MA, Brettingen LJ, Wake LA, Charles JF, Hernandez LL. 2023. In utero, lactational, or peripartal fluoxetine administration has differential implications on the murine maternal skeletal. Physiol. Rep. 11:e15837. Doi.1014814/phy2.15831. PMC:PMC10562136.

Domingues RR, Wiltbank MC, Hernandez LL. 2023. The antidepressant fluoxetine (Prozac) modulates estrogen signaling in the uterus and alters estrous cycles in mice. Mol. Cell Endocrinol. Jan 1;559:111783. PMCID:PMC10038119.

Domingues RR, Wiltbank MC, Hernandez LL. (2022). Pregnancy complications and neonatal mortality in a serotonin transporter null mouse model: insight into the use of selective serotonin reuptake inhibitor during pregnancy. Front. Med (Lausanne). 9:848581. PMCID: PMC8960382.

Selected Book Chapters

Collier RJ, Hernandez LL, Laporta J, Lauderdale J, Smith ZK, Vicini JL. 2020. Impacts on Human Health and Safety of Naturally Occurring and Supplemental Hormones in Food Animals. CAST Task Force. CAST: The Science Source for Food, Agricultural, and Environmental Issues. QTA2020-4-July 2020.

Hernandez LL, GE Dahl, and RJ Collier.  2017.  Regulation of the lactating mammary gland.  Large Dairy Herd Management.  3rd Edition. 

Selected Videos

Badger Talks Quick Pick: https://www.youtube.com/watch?v=AIb-rkQsBSk

The Role of the Mammary Gland in Governing Calcium Metabolism with Dr. Laura Hernandez

Undergraduate Courses

Biocore 485- Physiology

Graduate Courses

Graduate seminar (Endocrine and Reproductive Physiology)

MET 801 (Grant Writing)

Guest lecturer in several graduate courses

Co-Director UW Post-baccalaureate research Program

Director of Endocrine and Reproductive Physiology Graduate Program

Section Editor, Journal of Dairy Science

UW Committee on Faculty Rights and Responsibilities

Search Committee for the Vice Chancellor of Research

Research Advisory Committee for the Standards Committee of the Human Milk Banking Association

Standing Member NIH ICER study section

Faculty Mentor Committee Chair (5 faculty, member of 3 other faculty mentor committees)

Facilitator for Advanced Research Mentoring Practice Training (WISCIENCE)

Arthur J. and Ellen A. Maurer Extra Mile Award (2024)

ADSA Zoetis Physiology Award (2022)

Mid-Career Vilas Associates Award (2022)

CALS Pound Research Award (2021)

UW Vilas Faculty Fellowship (2018-2019)

ADSA Foundation Scholar Award in Production (2017)

Alfred Toepfer Faculty Fellow (2014)

 

 

U.S. Patent 8,133,916. Issued March 13, 2012. Control of Milk Production and Mammary Gland Involution.

U.S. Patent 9,585,870. Issued March 7, 2017. Compositions and methods for improving lactation.

Patent Pending: METHOD FOR PREVENTING ADVERSE PREGNANCY OUTCOMES DUE TO USE OF SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRI) DURING GESTATION