Laura Hernandez

    Hernandez Lab / Lactation Biology @ UW-Madison

    Professor Lactation Physiology; Affiliate Professor Obstetrics and Gynecology, Vice-Chair

    Research, Teaching

    Phone

    608-263-9867

    Office Location

    1675 Observatory Dr
    864A Animal Sciences
    Madison, WI 53706

    Photo of Laura Hernandez

    Post-Doctoral Fellow – Molecular and Cellular Physiology, University of Cincinnati (2008-2011)

    PhD University of Arizona (2008)

    Master’s of Science, New Mexico State University (2004)

    Bachelor’s of Science, New Mexico State University (2002)

    Selected Peer-Reviewed Articles

    Ambrogi M, Hernandez LL, Strand DW, Kumar S, Romero MF, Barasch J, Ridlon M, Keil Stietz KP, Vezina CM. A 5-HT-mediated urethral defense against urinary tract infections. Proc Natl Acad Sci U S A. 2025 Apr 22;122(16):e2409754122. doi: 10.1073/pnas.2409754122. Epub 2025 Apr 14. PMID: 40228121.

    Field SL, Arendt LM, Hernandez LL, Laporta J. Characterizing serotonin expression throughout bovine mammary gland developmental stages and its relationship with 17β-estradiol at puberty. PLoS One. 2025 Mar 25;20(3):e0319914. doi: 10.1371/journal.pone.0319914. PMID: 40131888; PMCID: PMC11936267.

    Domingues RR, Wiltbank MC, Hernandez LL, Adcock SJJ. Prenatal treatment with the antidepressant fluoxetine on maternal and neonatal behavior in sheep. Pediatr Res. 2025 Jan 14. doi: 10.1038/s41390-025-03799-3. Epub ahead of print. PMID: 39809853.

    Webster HH, Vang AL, Frizzarini WS, Cunha TO, Fricke HP, Moen ST, League LM, Lewandowski LR, Hernandez LLComparing the efficacy of serotonin and ethylene glycol tetraacetate on postpartum hypocalcemia. J Dairy Sci. 2025 Mar;108(3):2964-2980. doi: 10.3168/jds.2024-25338. Epub 2025 Jan 7. PMID: 39788187.

    Frizzarini WS, Campolina JP, Connelly MK, Fricke HP, Hernandez LLEffects of induced subclinical hypocalcemia in early-lactation Holstein cows without milking during infusion on parathyroid hormone and serotonin concentrations. JDS Commun. 2024 Jun 13;5(6):729-734. doi: 10.3168/jdsc.2024-0589. PMID: 39650027; PMCID: PMC11624329.

    Vang AL, Bresolin T, Frizzarini WS, Campolina JP, Menezes GL, Rosa GJM, Dorea JRR, Hernandez LL. Monitoring mammary gland development in preweaning dairy heifers using ultrasound imaging. JDS Commun. 2024 May 31;5(6):725-728. doi: 10.3168/jdsc.2024-0586. PMID: 39650009; PMCID: PMC11624348.

    Connelly MK, Rodney RM, Kuehnl J, Andrade JPN, Sonnewend Andrade F, Henschel S, Block E, Lean IJ, Hernandez LLThe effects of magnitude of calcium decline at the onset of lactation on serotonin dynamics and the serotonin-calcium axis. J Dairy Sci. 2025 Feb;108(2):1992-2004. doi: 10.3168/jds.2024-24836. Epub 2024 Oct 29. PMID: 39477066.

    Vang AL, Dorea JRR, Hernandez LLGraduate Student Literature Review: Mammary gland development in dairy cattle-Quantifying growth and development. J Dairy Sci. 2024 Dec;107(12):11611-11620. doi: 10.3168/jds.2024-25007. Epub 2024 Sep 28. PMID: 39343206; PMCID: PMC11614682.

    Vang AL, Frizzarini WS, Webster HH, Cunha TO, Nelson KM, Dorea JRR, Hernandez LLUltrasound-assisted minimally invasive technique for tissue collection from bovine mammary glands. Vet Med Sci. 2024 Nov;10(6):e70027. doi: 10.1002/vms3.70027. PMID: 39294888; PMCID: PMC11410675.

    Monteiro PLJ, Wiltbank MC, Frizzarini WS, Andrade JPN, Cabrera EM, Schoenfeld SG, Domingues RR, Hernandez LLHormonal profiles and biomarkers leading to parturition in cattle. Biol Reprod. 2024 Dec 12;111(6):1282-1296. doi: 10.1093/biolre/ioae133. PMID: 39221747.

    McNeil BK, Renaud DL, Steele MA, Cangiano LR, Olmeda MF, Villot C, Chevaux E, Yu J, Hernandez LL, Frizzarini WS, DeVries TJ. Effects of weaning and inactivated Lactobacillus helveticus supplementation on dairy calf behavioral and physiological indicators of affective state. J Dairy Sci. 2024 Dec;107(12):11363-11380. doi: 10.3168/jds.2023-24581. Epub 2024 Jul 26. PMID: 39067749.

    Desorcy-Scherer K, Zuniga-Chaves I, Reisner MA, Suen G, Hernandez LL. Investigating the influence of perinatal fluoxetine exposure on murine gut microbial communities during pregnancy and lactation. Sci Rep. 2024 Jun 14;14(1):13762. doi: 10.1038/s41598-024-62224-7. PMID: 38877103; PMCID: PMC11178873.

    Field SL, Galvan EA, Hernandez LL, Laporta J. Exploring the contribution of mammary-derived serotonin on liver and pancreas metabolism during lactation. PLoS One. 2024 Jun 5;19(6):e0304910. doi: 10.1371/journal.pone.0304910. PMID: 38837989; PMCID: PMC11152252.

    Frizzarini WS, Monteiro PLJ, Campolina JP, Vang AL, Soudah O, Lewandowski LR, Connelly MK, Arriola Apelo SI, Hernandez LLMechanisms by which feeding synthetic zeolite A and dietary cation-anion difference diets affect mineral metabolism in multiparous Holstein cows: Part I. J Dairy Sci. 2024 Jul;107(7):5204-5221. doi: 10.3168/jds.2024-24056. Epub 2024 Mar 14. PMID: 38490548.

    Frizzarini WS, Campolina JP, Vang AL, Lewandowski LR, Teixeira NN, Connelly MK, Monteiro PLJ, Hernandez LL. Mechanisms by which feeding synthetic zeolite A and dietary cation-anion difference diets affect feed intake, energy metabolism, and milk performance: Part II. J Dairy Sci. 2024 Jul;107(7):5222-5234. doi: 10.3168/jds.2024-24057. Epub 2024 Mar 14. PMID: 38490547.

    Selected Book Chapters

    Collier RJ, Hernandez LL, Laporta J, Lauderdale J, Smith ZK, Vicini JL. 2020. Impacts on Human Health and Safety of Naturally Occurring and Supplemental Hormones in Food Animals. CAST Task Force. CAST: The Science Source for Food, Agricultural, and Environmental Issues. QTA2020-4-July 2020.

    Hernandez LL, GE Dahl, and RJ Collier.  2017.  Regulation of the lactating mammary gland.  Large Dairy Herd Management.  3rd Edition. 

    Selected Videos

    Badger Talks Quick Pick: https://www.youtube.com/watch?v=AIb-rkQsBSk

    The Role of the Mammary Gland in Governing Calcium Metabolism with Dr. Laura Hernandez

    Undergraduate Courses

    AnSci/DySci 373- Animal Physiology with Dr. Wiltbank (Spring)

    Inter-Ag 488- CALS Honors in Research (Spring)

    Graduate Courses

    Graduate seminar (Endocrine and Reproductive Physiology)

    MET 801 (Grant Writing)

    Guest lecturer in several graduate courses

    Co-Director UW Post-baccalaureate research Program

    Director of Endocrine and Reproductive Physiology Graduate Program

    Journal of Dairy Science Editor in Chief

    UW Committee on Faculty Rights and Responsibilities

    Search Committee for the Vice Chancellor of Research

    Research Advisory Committee for the Standards Committee of the Human Milk Banking Association

    Standing Member NIH ICER study section

    Faculty Mentor Committee Chair (5 faculty, member of 3 other faculty mentor committees)

    Facilitator for Advanced Research Mentoring Practice Training (WISCIENCE)

    Arthur J. and Ellen A. Maurer Extra Mile Award (2024)

    ADSA Zoetis Physiology Award (2022)

    Mid-Career Vilas Associates Award (2022)

    CALS Pound Research Award (2021)

    UW Vilas Faculty Fellowship (2018-2019)

    ADSA Foundation Scholar Award in Production (2017)

    Alfred Toepfer Faculty Fellow (2014)

     

     

    U.S. Patent 8,133,916. Issued March 13, 2012. Control of Milk Production and Mammary Gland Involution.

    U.S. Patent 9,585,870. Issued March 7, 2017. Compositions and methods for improving lactation.

    Patent Pending: METHOD FOR PREVENTING ADVERSE PREGNANCY OUTCOMES DUE TO USE OF SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRI) DURING GESTATION