1675 Observatory Dr
Madison, WI 53706
Jess Reed is a Professor of nutrition, food and feed chemistry and international animal agriculture. Reed received his BSc (Animal Science, 1975) from Oregon State University, his MSc (Animal Science and International Agriculture, 1979), and Ph.D. (Animal Science and Nutrition, 1983) from Cornell. Reed’s Ph.D. dissertation field research took place in Kenya and was a study of the interaction between cattle, Grant’s and Thompson’s gazelle, kongoni (Coke’s hartebeest), and wildebeest in the utilization of range vegetation. His first position was as an Animal Nutritionist at the International Livestock Centre for Africa located in Addis Ababa, Ethiopia (1983 – 1989). UW-Madison recruited Reed in 1989 to become Associate Professor in Animal Nutrition and International Agriculture. During the first 2 years of his appointment, Reed was stationed in Gambia as an advisor to the Department of Livestock Services, as part of a grant from USAID to UW-Madison. Reed came to the UW-Madison campus in 1991 to build a research program on the effects of phytochemicals in foods and feeds on animal and human nutrition and health and to maintain a teaching and outreach program in international animal agriculture. Reed has experience in projects for animal agriculture and development in Africa (Burkina Faso, Ethiopia, Gambia, Kenya, Mali, Niger, and Zimbabwe), Asia (Bangladesh, China, India, Kazakhstan, Kyrgyzstan, Laos, Philippines, and Thailand) and Central and South America (Bolivia, Chile, Costa Rica, Honduras, Mexico, and Nicaragua).
The goal of Reed’s research program continues to be the development of new methods for testing hypotheses on the effects of phytochemicals in foods and feeds on the nutrition and health of humans and animals. The program is organized around three research themes: Phytochemistry, Mucosal Immunity, and Cardiovascular. The research cores evolved from our interest in the effects of plant oligomeric polyphenolic compounds (Tannins) on animal and human disease. Our research combines analytical chemistry, in vitro research with mammalian cell culture and bacteria, in vivo research (mice, rats, swine, and sheep) and clinical studies. Reed is also an inventor of new technologies from discoveries made in our research program that is assigned to the Wisconsin Alumni Research Foundation (WARF) for patent protection and licensing.
Selected Peer-Reviewed Articles
Gullickson ER, Krueger CG, Birmingham A, Maranan M, Reed JD. Development of a cranberry standard for quantification of insoluble cranberry (vaccinium macrocarpon ait.) proanthocyanidins. Journal of agricultural and food chemistry. 2020; 68:2900-2905
Alfaro-Viquez E, Esquivel-Alvarado D, Madrigal-Carballo S, Krueger CG, Reed JD. Proanthocyanidin-chitosan composite nanoparticles prevent bacterial invasion and colonization of gut epithelial cells by extra-intestinal pathogenic escherichia coli. Int J Biol Macromol. 2019;135:630-636.
Bekiares N, Krueger CG, Meudt JJ, Shanmuganayagam D, Reed JD. Effect of sweetened dried cranberry consumption on urinary proteome and fecal microbiome in healthy human subjects. Omics: a journal of integrative biology. 2018;22:145-153. PMCID: 5810433
Barone CD, Zajac AM, Manzi-Smith LA, Howell AB, Reed JD, Krueger CG, Petersson KH. Anthelmintic efficacy of cranberry vine extracts on ovine haemonchus contortus. Veterinary parasitology. 2018;253:122-129. PMCID: 6056019
Alfaro-Viquez E, Esquivel-Alvarado D, Madrigal-Carballo S, Krueger CG, Reed JD. Cranberry proanthocyanidin-chitosan hybrid nanoparticles as a potential inhibitor of extra-intestinal pathogenic escherichia coli invasion of gut epithelial cells. Int J Biol Macromol. 2018;111:415-420.
Williams AR, Klaver EJ, Laan LC, Ramsay A, Fryganas C, Difborg R, Kringel H, Reed JD, Mueller-Harvey I, Skov S, van Die I, Thamsborg SM. Co-operative suppression of inflammatory responses in human dendritic cells by plant proanthocyanidins and products from the parasitic nematode trichuris suis. Immunology. 2017;150:312-328. PMCID: 5290246
Carballo SM, Haas L, Krueger CG, Reed JD. Cranberry proanthocyanidins – protein complexes for macrophage activation. Food & function. 2017;8:3374-3382.
Bekiares NA, Chen AS, Shanmuganayagam D, Meyers AD, Crenshaw TD, Krueger CG, Reed JD. Effect of caloric restriction on metabolic dysfunction of young rapacz familial hypercholesterolemic swine (sus scrofa). Comparative medicine. 2017;67:508-517. PMCID: 5713166
Polewski MA, Krueger CG, Reed JD, Leyer G. Ability of cranberry proanthocyanidins in combination with a probiotic formulation to inhibit in vitro invasion of gut epithelial cells by extra-intestinal pathogenic e. Coli. J Funct Foods. 2016;25:123-134.
Madrigal-Carballo S, Haas L, Vestling M, Krueger CG, Reed JD. Non-covalent pomegranate (punica granatum) hydrolyzable tannin-protein complexes modulate antigen uptake, processing and presentation by a t-cell hybridoma line co-cultured with murine peritoneal macrophages. International journal of food sciences and nutrition. 2016:1-9.
Krueger CG, Chesmore N, Chen X, Parker J, Khoo C, Marais JPJ, Shanmuganayagam D, Crump P, Reed JD. Critical reevaluation of the 4-(dimethylamino)cinnamaldehyde assay: Cranberry proanthocyanidin standard is superior to procyanidin a2 dimer for accurate quantification of proanthocyanidins in cranberry products. J Funct Foods. 2016;22:13-19.
Blumberg JB, Basu A, Krueger CG, Lila MA, Neto CC, Novotny JA, Reed JD, Rodriguez-Mateos A, Toner CD. Impact of cranberries on gut microbiota and cardiometabolic health: Proceedings of the cranberry health research conference 2015. Advances in nutrition. 2016;7:759S-770S. PMCID: 4942875
Porras AM, Shanmuganayagam D, Meudt JJ, Krueger CG, Hacker TA, Rahko PS, Reed JD, Masters KS. Development of aortic valve disease in familial hypercholesterolemic swine: Implications for elucidating disease etiology. Journal of the American Heart Association. 2015;4:e002254. PMCID: 4845146
Feliciano RP, Krueger CG, Reed JD. Methods to determine effects of cranberry proanthocyanidins on extraintestinal infections: Relevance for urinary tract health. Molecular nutrition & food research. 2015;59:1292-1306.
Feliciano RP, Heintz JA, Krueger CG, Vestling MM, Reed JD. Fluorescent labeling of cranberry proanthocyanidins with 5-([4,6-dichlorotriazin-2-yl]amino)fluorescein (dtaf). Food chemistry. 2015;166:337-345.
Selected Conference Proceedings
Krueger, CG, Alfaro-Viquez, E, Madrigal-Carballo, S, Reed, JD. Tannin-Chitosan Composite Nanoparticles as an Alternative to Antibiotics. 249th American Chemical Society National Meeting, March 22-26, 2015, Denver, CO
Madrigal-Carballo, S, Araya-Matey, J, Esquivel-Alvarado, D, Alfaro-Viquez, E, Krueger, CG, Reed, JD. Secondary liposomes stabilized by the electrostatic deposition of chitosan-tannin composites as potential delivery systems for proteins. 249th American Chemical Society National Meeting, March 22-26, 2015, Denver, CO
Madrigal-Carballo, S,. Alfaro-Viquez, E., Esquivel-Alvarado, D., Chianelli, F., Leon, C., Krueger, C., Reed, J. Tannin-Chitosan composite materials for transdermal delivery of cannabidiol. XXIX International Conference on Polyphenols and 9th Tannin Conference, July 16-20, 2018, Madison, WI
Madrigal-Carballo, S., Alfaro-Viquez, E., Krueger, C., Reed, J. Nanotechnology as a useful tool for polyphenol research and development. XXIX International Conference on Polyphenols and 9th Tannin Conference, July 16-20, 2018, Madison, WI
Gullickson, E., Birmingham, A., Krueger, C., and Reed, J. The utilization of a cranberry (Vaccinium macrocarpon Ait.) proanthocyanidin standard to quantify insoluble proanthocyanidins by butanol-hydrochloric acid method. XXIX International Conference on Polyphenols and 9th Tannin Conference, July 16-20, 2018, Madison, WI
Esquivel-Alvarado, D., Alfaro-Viquez, E., Urena-Saborio, H., Rodriguez, G., Madrigal-Carballo, S., Krueger, C., Reed, J. Characterization of Proanthocyanidin profile of tropical cranberries (Vaccinum consangunium, Vaccinum floribundum, and Vaccinum talamancense) from Costa Rica. XXIX International Conference on Polyphenols and 9th Tannin Conference, July 16-20, 2018, Madison, WI
Esquivel-Alvarado, D., Alfaro-Viquez, E., Madrigal-Carballo, S., Krueger, C., Berres, M., Reed, J. Computer-based Polyphenol-Fingerprinting™ as innovative analytic method for proanthocyanidins authentication in natural products. XXIX International Conference on Polyphenols and 9th Tannin Conference, July 16-20, 2018, Madison, WI
Madrigal-Carballo, S., Polewski, M., Wedde, N., Esquivel-Alvarado, D., Krueger, C., and Reed, J. Fluorescently Labeled 5-([4,6-dichlorotriazin-2-yl]amino) Fluorescein Cranberry Proanthocyanidins (DTAF-PAC) as a Tool to Understand in vitro Biological Interactions with Extra-intestinal Pathogenic Escherichia coli (ExPEC). XXIX International Conference on Polyphenols and 9th Tannin Conference, July 16-20, 2018, Madison, WI
Alfaro-Viquez, E., Esquivel-Alvarado, D., Polewski, M., Madrigal-Carballo, S., Krueger, C., and Reed, J. Cranberry proanthocyanidin-chitosan composite nanoparticles as potential nanoantibiotics against extra-intestinal pathogenic Escherichia coli. XXIX International Conference on Polyphenols and 9th Tannin Conference, July 16-20, 2018, Madison, WI
Polewski, M., Wedde, N., Esquivel-Alvarado, D., Krueger, C., and Reed. J. Isolation and Characterization of Blueberry Polyphenolic Components and their Effects on Gut Barrier Function using an In Vitro Model of Gut Barrier Dysfunction. XXIX International Conference on Polyphenols and 9th Tannin Conference, July 16-20, 2018, Madison, WI
Gullickson, E., Krueger, C., Polewski, M., Wedde, N., Reed, J. (2018, September). The effect of cranberry proanthocyanidins on gut barrier function and inflammation in an in vitro cell co-culture model. Poster session presented at the 36th Annual Fall Symposium for the Wisconsin Society for Parenteral and Enteral Nutrition, Summit, WI.
Gullickson, E., Krueger, C., Polewski, M., Wedde, N., Reed, J. The Effect of Cranberry Proanthocyanidins on Gut Barrier Function and Inflammation in an In Vitro Cell Co-Culture Model. American Society for Parenteral and Enteral Nutrition 2019 Nutrition Science and Practice Conference, March 23 to 26, 2019, Phoenix AZ.
Polewski, M., Wedde, N., Krueger, C., and Reed, J. Evaluation of Cranberry Proanthocyanidins in an In Vitro Model of Gut Barrier Dysfunction. 8th Biennial Berry Health Benefits Symposium May 7th-9th, 2019, Portland, OR
AN SCI/DY SCI 370 – Livestock Production and Health in Agricultural Development (3 credits, Fall)
Course Description: Physical, biological and social nature of animal agriculture systems and their improvement in developing countries; analysis of the state of livestock research and development in the developing countries and the world role of U.S. animal agriculture.
Requirements: An Sci/DY SCI/AN SCI 101 or cons inst
Reed contributes to the international dimension of the animal and dairy sciences curriculum by giving 2 lectures to Animal Science 101 during the fall semester and 1 Contributed lecture in Introduction to Global Health, Nutritional Sciences 203, which are high enrollment courses. These lectures give the students an appreciation of the importance of applying science to animal agriculture in developing countries in relationship to economic development.
Reed also lectures on the chemistry of plant cell wall and fiber in the graduate ruminant nutrition course, Ruminant Nutritional Physiology II. These lectures cover the structure, biosynthesis and digestion of plant cell wall polysaccharides and lignin as related to nutrition.